Explain self-recognition, tolerance and describe specific immune system disorders.

Using the title “I Am Defended” and a method of your choice explain how humans are defended from infection.

Your explanation needs to include

-Non-specific and specific immunity,

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-Passive and active Vaccination with discussion of the safety and effectiveness of named examples.

– Isolation and herd immunity.

1. Understand non-specific defences against disease.

1.1 Describe the first and second lines of defence giving specific examples.

2. Understand specific immunity.

2.1 Explain the third line of defence, acquired (adaptive or specific) immunity.

2.2 Explain self-recognition, tolerance and describe specific immune system disorders.

3. Understand the biology of vaccination.

3.1 Describe the categories of acquired immunity including natural, artificial, passive and active.

3.2 Explain the immune response to vaccination including immunological memory, analysing data to evaluate the benefits of vaccination.

3.3 Discuss the concept of herd immunity, vaccination programmes and factors effecting vaccine uptake.

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